Use in children and adolescents < 18 years, efficacy and safety of Parlodel been established for children and adolescents with and acromegaly prolaktomami over 7 years. The testosterone enanthate vs cypionate experience of the drug in children younger than 7 years old is restricted in the clinical research and medical practice tolerated in adults and children is the same. Given the difficult to predict the sensitivity of children and adolescents, should be careful in appointing a drug of this category of patients. Use in patients > 65 years Number of patients 65 years of age and older in clinical studies was insufficient to evaluate the possible differences of treatment response parlodel compared with younger patients.
However, clinical testosterone enanthate vs cypionate trials and medical practice tolerability in patients > 65 years of age and younger was the same. Given the difficult predictable tolerability in patients > 65 years, caution should be exercised when administering the drug in this category of patients. The use in postpartum period in women taking Parlodel in the postnatal period for suppression of lactation have been rare cases of serious adverse events: hypertension, myocardial infarction, seizures, stroke or mental disturbances. In some patients the development of seizures or cerebrovascular events were preceded by severe headache and / or transient visual disturbances. Although a causal relationship between these phenomena with Parlodel reception is not set, in women taking medication for postpartum lactation suppression, as well as in patients receiving Parlodel under any other indications should be controlled blood pressure (BP). With the development of hypertension or severe, progressive or persistent headache (accompanied and unaccompanied by the visually impaired), or of a violation of the central nervous system, Parlodel should be abolished and conduct examination of the patient immediately. Special care is required to comply with the appointment of Parlodel in patients who received recently or continue to take drugs that affect blood pressure, such as vasoconstrictor drugs (sympathomimetics or ergot alkaloids including ergometrine or metilergometrin). The women in the postpartum period is not recommended the simultaneous use of Parlodel with vasoconstrictor agents.
Pregnancy and lactation
In patients wishing to conceive, after confirmation of pregnancy receiving Parlodel, like other drugs, should be abolished except where the need to continue treatment for a medical condition. Cancel Parlodel during pregnancy does not increase the frequency of its spontaneous abortion. Clinical experience shows that the use of Parlodel during pregnancy has no adverse effect on its course or outcome.
If you cancel Parlodel in pregnant women with pituitary adenoma is necessary to carry out careful monitoring of the patients throughout the duration of pregnancy. In the event of signs of a marked increase in prolactinoma, eg headache or visual field constriction, Parlodel treatment may be resumed or carried out surgery.
Since Parlodel inhibits lactation, it should testosterone enanthate vs cypionate not be administered to nursing mothers.
DOSAGE AND ADMINISTRATION
Parlodel should be taken orally with meals. Menstrual disorders, female infertility Assign to 1.25 mg (1/2 tablet) 2-3 times a day; if the effect is not sufficient, the dose is gradually increased to 5-7.5 mg per day (3.2 multiplicity of reception times / day). Treatment is continued until the normalization of the menstrual cycle and / or restoration of ovulation. If necessary, for preventing relapse, treatment may continue for several cycles. Hyperprolactinemia in men Assign 1.25 mg (1/2 tablet) 2-3 times a day, gradually increasing the dose 5-10 mg (2-4 tablets) per day. Prolaktinomy Assign to 1.25 mg (1/2 tablet) 2-3 times a day with a gradual increase in dose selection and dosing, ensuring an adequate reduction in plasma prolactin concentration. The maximum recommended dose for children and adolescents aged 7-12 years of age is 5 mg / day, for at the age of 13-17 years -. 20 mg Acromegaly The initial dose is at 1.25 mg (1/2 tablet) 2-3 times a day, thereafter, depending on the clinical response and tolerability, the daily dose is gradually increased up to 10-20 mg (4-8 tablets).
The maximum recommended dose for children and adolescents aged 7-12 years of age is 10 mg / day, for at the age of 13-17 years – 20 mg.Inhibition of lactation for medical reasons on the first day prescribe on 1.25 mg (1/2 tablet) 2 times (during eating breakfast and dinner), then within 14 days – 2.5 mg (1 tablet), 2 times a day. To prevent the start of lactation the drug should be started within a few hours after birth or abortion, but only after stabilization of vital functions. After 2 or 3 days after the drug is sometimes a small milk production. It can be eliminated by resuming the drug at the same dose for 1 more week. Starting puerperal mastitis the first day prescribe on 1.25 mg (1/2 tablet) 2 times (during meal at breakfast and supper), then within 14 days – by 2.5 mg (1 tablet), 2 times a day. Additionally prescribe an antibiotic. Parkinson’s disease In order to ensure optimal tolerability during the first week testosterone enanthate vs cypionate of treatment should be started with a low dose of 1.25 mg (half tablet) 1 every day (preferably in the evening). For the selection of the individual minimum effective dose to increase the number received the drug should be slowly, by “titration.” Dose increases gradually – each week the daily dose increased to 1.25 mg; the daily dose is divided into 2-3 doses. Adequate therapeutic response is achieved by an average of 6-8 weeks of treatment. If no clinical effect after 6-8 weeks of treatment may further increase the daily dosage of 2.5 mg per week. Typically, the therapeutic dosage range for bromocriptine mono- or combination therapy is from 10 mg to 40 mg per day, but some patients may require more higher doses. If the selection of doses adverse reactions occur, the daily dose should be reduced and maintained at a lower level of at least 1 week. When coping with side effects, the dose can once again increase. Patients with movement disorders in patients receiving levodopa, it is recommended before the application of Parlodel to reduce the dose of levodopa. After a satisfactory clinical effect in the treatment of Parlodel can be carried out further gradual reduction in the dose of levodopa. Some patients taking Parlodel, possible full cancellation of levodopa. boldabol bodybuilding supplements shop omega 3 kapseln einnahme bodybuilding